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English words and Examples of Usage
use "mediating" in a sentence
Deputy Secretary of State Strobe Talbott (a sometime Slate contributor), who was mediating the peace talks.
senator who is mediating the talks.
By 1968, that annus horribilis when Johnson cracked from the pressure of mediating an increasingly centripetal Democratic Party and Kennedy fell to an assassin's bullet, two political ideal-types had solidified: a "silent majority" who supported Johnson's war on Vietnam and voted in Richard Nixon, and a "new class" of liberal professionals and youth who supported Johnson's war on poverty but detested everything Richard Nixon represented.
Such a system might blindly try out variant patterns of synthesis until it could establish a self-sustaining web linking the carbohydrates, the enzymes, and certain protein receptors mediating the linkage between unconditioned and conditioned stimulus, then maintain that linkage by positive feedback loops.
Thus an alteration in the PG E 2 /F 2?
ratio plays an important role in mediating IDO's effects on cell growth and morphology.
Thus, the role of cPLA 2 phosphorylation in mediating AA release remains unclear.
Similar structures also occur in primary keratinocytes mediating intercellular adhesion [ 31].
To determine whether the RING finger plays a role in mediating nuclear import, we mutated two key zinc-binding cysteine residues at the RING finger domain of GFP-N346 (C158A/C161A, N346 RINGmut) to destroy the RING finger structure (Fig 7A).
Discussion Evidence for a role of COP1 in protein ubiquitination in vivo Because of its role in mediating the degradation of HY5, HYH, and possibly other transcription factors in Arabidopsis [ 4 5 ] and the presence of a RING finger domain and a WD-40 domain, AtCOP1 has been proposed to function as a RING-finger type ubiquitination E3 ligase, by recruiting E2 through its RING-finger domain and binding to the substrates through the WD-40 repeats [ 4 43 ] .
Interestingly in MmCOP1, the site matching the AtCOP1 NLS is found to be important for targeting the nuclear localized MmCOP1 deletion construct N346 to speckles rather than mediating nuclear import (Fig 8).
It has been suggested that the involvement of Ig-related molecules in tissue interactions is more primitive than their involvement in the immune system and the immune functions evolved from the sets of molecules mediating tissue interactions [ 25].
In addition, homologs of ld130 are also found in gp64 -containing viruses, although they do not appear to be capable of mediating low-pH-dependent membrane fusion (Pearson et al, unpublished).
Thus, at these genes, Mig1, Mig2 and Nrg1 are partially redundant for mediating repression by glucose.
Cytokine production is decreased in the Hoxa3 +/- Pax1 -/-fetal thymus Cytokines produced by TECs are good candidates for mediating at least some of these changes in thymocyte proliferation and apoptosis in the Hoxa3,Pax1 compound mutants.
However before this picture about the involvement of NK cells in LAK activity emerged there existed considerable controversy regarding the type of effector cells mediating this activity, particularly concerning the relative contributions by the two lymphocyte populations, NK Vs cytotoxic T cells [ 5 6 7 8 9 ] .
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