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Example Sentences for "antagonists"

California, where Microsoft antagonists Netscape, Oracle, and Sun live, has signed on.

Kennedy being elevated, for better or for worse, to the role of standard-bearer for a generation repulsed by America's imperial presumptions, the antagonists became symbols for opposing forces larger than either man could discern.

But just when you start to get impatient with the plodding, one-thing-after-another style of narration, there's a shocker that blows you into the movie's last act, and then a scene in which a couple of former antagonists figure out what stinks and join forces in an abandoned motel to stave off an army of bad guys.

A more plausible explanation is probably that Kazan, now 89, has outlived most of his antagonists and that the fury of the rest has lost its edge.

London's Independent listlessly concludes that "triumph was not on the agenda at Rambouillet yesterday, only weariness and relief that the show had been kept on the road after 17 days of discussions at which the two antagonists did not once negotiate with each other directly.

Rather than let each woman decide whether to come forward, Clinton's antagonists dragged her onstage.

Insurrection boasts the only space battle in film history in which the antagonists sing Gilbert and Sullivan while firing on each other--which is reason enough to go warp factor 9 to movie number 10.

txt Background With the publication of the Antihypertensive and Lipid-Lowering Treatment to prevent Heart Attack Trial (ALLHAT), the role of peripheral alpha-1 antagonists in the treatment of hypertension has become controversial.

Prior to this publication, there had been no obvious suggestion of a mechanism by which peripheral alpha-1 antagonists in general or doxazosin in particular would be inferior to chlorthalidone or would specifically cause CHF.

Nonetheless, there has been a large body of literature dedicated to the positive effects of peripheral alpha-1 antagonists on surrogate endpoints such as cholesterol levels and tolerability.

Methods Medline and the Cochrane databases were used to identify English-language papers on peripheral alpha-1 antagonists in studies targeting cardiovascular endpoints, background physiologic literature, or any studies suggesting mechanisms leading to an inferior performance in cardiovascular endpoints.

Results Use in Hypertension and Prostatism Evidence suggests that alpha-1 antagonists are frequently prescribed for hypertension, but there are few published data concerning the prevalence of the routine use of peripheral alpha-1 antagonists, the prevalence according to co-morbid conditions such as benign prostatic hypertrophy and the usual duration of therapy.

In the sixth report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC VI), peripheral alpha-1 antagonists are recommended not only as second-line anti-hypertensive therapy after low-dose diuretics and beta blockers, but also for specific indications such as therapy in men with hypertension and prostatism [ 2 ] .

Alpha-1 antagonists represent effective therapy for prostatism, and fifty percent of men have histologic evidence of BPH by 60 years of age [ 3 4 ] .

Weight and Fluid Status Peripheral alpha-1 antagonists were consistently associated with fluid retention.

Peripheral alpha-1 antagonists were associated with perturbations in neurohormonal levels in various studies.

In particular, peripheral alpha-1 antagonists are associated with an increase in plasma norepinephrine in diverse patient populations, as summarized in Table 3.

Hooper proposed that peripheral alpha-1 antagonists alter cellular repair mechanisms, possibly causing cardiac damage.

At that time, the results of the ALLHAT trial were unexpected, given the potential association between high dose diuretics and the risk of sudden death [ 22 ] , and the favorable effect of peripheral alpha-1 antagonists on lipid profiles [ 14 ] .

Comparing data from other studies suggests the possibility that the beneficial effects of peripheral alpha-1 antagonists for lowering blood pressure may be nullified by a negative effect, or that other antihypertensives have positive actions beyond their antihypertensive effects.



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