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Sentences for "antagonizes"
It antagonizes the Senate.
Next, whether TGF-ß1 antagonizes the function of Hyal-1 and Hyal-2 in growth regulation was examined.
Their results show that NF-AT is a downstream target of the Wnt/Ca 2+pathway and antagonizes the Wnt/beta-catenin pathway in Xenopus embryos.
In the present study, using laser scanning confocal microscopy, we show that the ER calcium pool is a target of mefloquine in rat neurons, as, under calcium free conditions, the drug induces elevations in intracellular calcium concentrations and antagonizes the pharmacological effect of thapsigargin, a known inhibitor of the ER calcium pump.
Thapsigargin antagonizes the disruptive effect of mefloquine on calcium homeostasis and protects neurons from cellular injury Pre-treatment with thapsigargin (4 µM) antagonised both the initial rise in intracellular calcium attributable to the effect of mefloquine on the ER calcium store, and the subsequent sustained influx of external calcium (Figure 4).
Our data show that, in nominally calcium free medium, mefloquine induces a transitory elevation of cytoplasmic calcium levels and antagonizes a similar effect induced by thapsigargin.
However, this discrepancy is expected, because DIDS antagonizes a chloride influx pathway in pig GC, and chloride efflux pathways in Leydig cells.
Because RU486, along with antagonizing the GR antagonizes the PR, some of the RU486 benefit may be due to antagonism of progesterone effects.
This was somewhat surprising, since MAPK pathways do not activate JunB [ 29] and in some systems JunB antagonizes transcriptional activation by c-Jun [ 30].
Thus, it is tempting to speculate that IL-1 antagonizes the effects of TGF-ß by blocking expression of essential signaling intermediates, such as SMAD4.
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