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Sentences for "anticancer"
In contrast, Hyal-1 and Hyal-2 did not enhance L929 cell death by anticancer drugs such as daunorubicin, actinomycin D, staurosporine and camptothecin.
In similar experiments, the effect of transient expression of Hyal-1 and Hyal-2 on cellular sensitivity to anticancer drugs was examined.
This assay measures the ability of TOP1 to cleave end-labeled DNA substrates in the presence of the anticancer drug camptothecin, which blocks the ligation step of the cleavage /religation reaction of TOP1.
Similarly, in studying the effect of an intense chemotherapeutic regimen for cancer on survival, the type of antibiotic should not change of over time, as new and more effective antibiotics could lower treatment-related mortality irrespective of the efficacy of the anticancer regimen.
txt Background Extensive bone marrow infiltration with cancer cells and anticancer therapy lead to immune incompetence in children with cancer [ 1 2 ] .
In patients undergoing conventional anticancer therapy without BMT, the data focusing on EBV, CMV or HHV-6 infection are scarcely documented and mostly reported as individual cases [ 16 17 18 19 ] .
Inclusion criteria for patients included: presence of cancer, serology of EBV and CMV at least at the time of cancer diagnosis (pre-treatment sample) and 2 months after the end of anticancer therapy (post-treatment sample).
Children with cancer undergoing BMT, human immunodeficiency virus positive children, and children who died while on anticancer therapy were excluded from the study.
During anticancer therapy, samples of peripheral blood for serology and LH DNA study were taken as clinically indicated in the following situations: (1) FN (defined as a single episode of oral temperature ?
38.
Based on serology, we were able to demonstrate the rate of primary infection and reactivation of LH in most of the patients during anticancer treatment.
One patient had coinfection of EBV and HHV-6 during anticancer treatment detected by PCR [EBV (+++) positive, HHV-6 (+)] with serological evidence of primary EBV infection and reactivation of HHV-6.
EBV and CMV infection occurred in almost 50% of children younger then 6 years during anticancer treatment.
On the other hand, children in all age groups reached similar EBV and CMV seropositivity levels after anticancer treatment comparing to healthy adult controls.
In an effort to illustrate the role of leukodepleted blood transfusions in transmission of LH infection in pediatric oncology patients we studied both populations: a population of patients treated with leukodepleted irradiated blood products and a population of patients that did not required any blood transfusion during anticancer treatment.
Unlike anti-estrogens, such as tamoxifen or raloxifene, ligands targeted against the RAR isoforms can present anticancer activity against both estrogen receptor positive and negative breast tumor cells [ 1].
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