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Sentences for "antimalarial"
mexicana produce antimalarial drugs [ 28 29 30 ] , and artemisinin (from A.
The structural and biochemical properties of PfPP5 described herein are hallmarks of the PP5 class, and thus establish PfPP5 as a likely player in parasitic signal transduction, and hence a potential target for antimalarial drug design.
No clinical diagnostic criteria are both sensitive and specific for malaria, an undifferentiated febrile illness [ 5 ] which may result in the erroneous treatment of millions of non-malaria cases with antimalarial drugs in the absence of diagnostic malaria microscopy.
Excessive antimalarial drug use is costly, propels the emergence of drug resistant parasites, speeds the obsolescence of affordable drugs and retards malaria control [ 6 ] .
This field study appraised the performance of the rapid diagnostic test in assessing the impact of antimalarial intervention measures in villages of two adjacent Primary Health Centre's of district Mandla, central India.
txt Background Mefloquine is a prophylactic antimalarial drug that is also used for malaria chemotherapy.
txt Background Mefloquine (Lariam) is a prophylactic antimalarial that is also used for malaria chemotherapy.
In areas where mosquito abatement has failed, chemotherapy, consisting of a limited selection of antimalarial agents, is the only defense against this disease.
The increase in drug resistance throughout the malaria endemic regions is cause for great concern and calls for the development of new antimalarial measures, which would involve a larger variety of drug targets as well as a wider array of vaccine strategies (reviewed in [ 2, 3]).
Further understanding of cellular physiology of this parasite including basic metabolic functions and the intricate interactions between the parasite cell and human host immune system will be a key step in uncovering new targets for antimalarial drug discoveries and vaccine development.
Two weeks before the third dose was given, all the volunteers received antimalarial drugs to clear blood-stage P.
The inappropriate use of antimalarials during the past century has contributed to this increase in resistance.
They also suggested that antimalarials should be judged not just on their impact on recrudescence but also on their impact on the risk of new infections after therapy.
Artemisinins are highly attractive antimalarials, but when used as monotherapy, they have a high risk of recrudescence and hence must be combined with other antimalarials to achieve maximum efficacy.
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