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Sentences for "antirheumatic"
Etanercept (sTNFR:Fc) and infliximab (chimeric anti-TNF monoclonal antibody) have been shown to be efficacious in the treatment of patients with RA for whom treatment with at least one disease-modifying antirheumatic drug had previously failed [ 11, 12], both of these biologicals have been approved by regulatory agencies for the treatment of patients with RA.
All patients had to have had at least one failed trial of a disease-modifying antirheumatic drug (DMARD) and had to have at least 10 painful and 10 swollen joints at entry.
Abbreviations ACR = American College of Rheumatology, CRP = C-reactive protein, DMARD = disease-modifying antirheumatic drug, IL = interleukin, NF = nuclear factor, RA = rheumatoid arthritis, rhIL-11 = recombinant human IL-11, TNF = tumor necrosis factor.
Discussion Currently, MTX is the most widely used disease-modifying antirheumatic drug for the treatment of RA.
All patients in the group were receiving disease-modifying antirheumatic drugs and were clinically stable.
Patients with RA were older, had more tender and swollen joints, were rheumatoid factor positive, and were more likely to be on disease-modifying antirheumatic drug therapy than were non-RA patients.
01), and more disease modifying antirheumatic drug therapy (1.
7 disease modifying antirheumatic drugs, P <0.
01), and more disease modifying antirheumatic drug therapy (1.
7 disease modifying antirheumatic drugs, P <0.
In particular, there was a significantly higher prevalence of radiographic erosions in the anti-Sa-positive RA patients compared with the rest of the RA population, despite the fact that the anti-Sa-positive patients had received significantly higher doses of prednisone and more disease modifying antirheumatic drug therapy.
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