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' Example 2 A multicenter, randomized, open-label, parallel-design study to compare the treatment effect of niacin and atorvastatin (for 12 weeks) on lipoprotein subfractions in patients with atherogenic dyslipidemia [ 2 ] .
The characteristics of the metabolic syndrome include atherogenic dyslipidemia, a prothrombotic state, insulin resistance, hypertension, and abdominal obesity [ 3 4 ] .
Each abnormality promotes atherosclerosis independently, but when clustered together, these metabolic disorders are increasingly atherogenic and enhance the risk of cardiovascular morbidity and mortality [ 1 ] .
txt Introduction In addition to the role of smoking in cancer initiation and promotion, cigarette smoking accelerates atherogenic cardiovascular disease in both a dose- and a duration-dependent manner through several concurrent pathways.
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