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Sentences for "axon "
Microarrays were scanned in both Cy3 and Cy5 channels with an Axon GenePix scanner (Foster City, CA) with a 10 µm resolution.
Not surprisingly, many of these mutants also show defects in axon extension, bundling and pathfinding.
unc-129 is expressed dorsally and loss of UNC-129 function disrupts dorsal axon migrations.
We conclude, therefore, that the sequence is sequestering a factor that helps control ALM migrations and PLM axon outgrowth.
All ALMs that showed defects in axon morphology were anterior to position 6.
Perhaps ALMs positioned anterior to position 6 sometimes fail to find their normal axon guidance cues.
Interestingly, some of these anteriorly positioned ALMs had axon morphologies similar to BDU neurons.
These cells, being deprived of their own axon guidance cues, may have followed the BDU axon guidance cues.
Because this element appeared to sequester a factor involved in ALM migration and PLM axon outgrowth, it is probably a mec-3 control element.
The nerve fiber layer, composed of retinal ganglion cell axons was not evident even adjacent to the scleral foramen where it is normally substantially thickened due to axon convergence on the optic nerve.
Further experiments are necessary to determine if BMP4 modulates retinal ganglion cell axon sprouting, elongation, targeting or maintenance, or if BMP4 regulates events in optic nerve glia that affect these processes.
Exogenous BMP7 enhances dendrite but not axon growth in embryonic rat sympathetic neurons [ 54 ] and hippocampal neurons [ 55 ] .
Ectopic BMP4 can lead to the upregulation of Tbx5 in the retina, and Tbx5 misexpression results in altered retinal ganglion cell axon projections to the tectum [ 56 ] .
txt Background Protein tyrosine phosphorylation regulates many important cellular functions including signal transduction, growth, differentiation, cell adhesion and axon guidance.
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