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Example Sentences for "biosynthesis "


To date, the genes that have been shown to be responsive to regulation by FXR encode proteins involved in the biosynthesis and transport of bile acids [ 13 ] .

The DNA sequences were analyzed by the Biosynthesis and Sequencing Facility in the Department of Biological Chemistry at Johns Hopkins University.

195) catalyzes the following reaction: cinnamyl alcohol + NADP += cinnamaldehyde + NADPH (but it can also act on coniferyl alcohol, sinapyl alcohol and 4-coumaryl alcohol) in the flavonoid, stilbene and lignin biosynthesis pathways [ 40 42 ] .

Such a trade-off may well be at the basis of the genetic correlation between flowering time and cell wall biosynthesis observed in maize.

Discussion The results from this study indicate that changes in cell wall biosynthesis affect flowering dynamics in sorghum.

If the correlation between flowering dynamics and cell wall biosynthesis were spurious, mutations affecting cell wall composition in evolutionarily related species with different flower morphology would not show association with flowering dynamics.

Mutations in lignin biosynthesis may affect the effective concentration of such molecules, which could include dehydrodiconiferyl alcohol glucosides (DCGs).

Five of these were eukaryotic sequences of unknown function, five others were eukaryotic MSAE proteins, and one was a ThiF ORF within an operon containing two other thiamin biosynthesis genes in Erwinia amylovora [ 31 ] .

Here we discover a requirement of adenine biosynthesis for high-level dinucleoside polyphosphate accumulation in the absence of the Fhit homolog in S.

Cholesterol oxides are inhibitors of HMG-CoA reductase, the key enzyme of cholesterol biosynthesis pathway [ 47 ] .

In addition, the targeted knockout of the ALDH1A2 gene in mice results in a significant decrease in retinoic acid biosynthesis and early embryo death [ 18 ] .

Our long-term goal is to use DPAB to investigate the role of ALDH1A1 in retinoic acid biosynthesis at different stages of hematopoiesis.

Characterization of these mutants reveals that the sis5 [ 46 ] , sun6 [ 50 ] , gin6 [ 49 ] and isi3 [ 45 ] mutants are allelic to the abscisic acid insensitive mutant abi4 [ 51 ] and the sis4 [ 46 ] , isi4 [ 45 ] and gin1 [ 45 ] mutants are allelic to the abscisic acid biosynthesis mutant aba2 [ 52 ] .

The link between 3-MGC aciduria and mitochondrial dysfunction may involve failure of mitochondrial uptake of 3-MGC acid or potentially defective ubiquinone biosynthesis leading to increased levels of mevalonate in the mevalonate shunt pathway with subsequent increased synthesis of 3-MGC acid [ 27 ] .

All statins limit cholesterol biosynthesis by inhibiting the committed step in the biosynthesis of isoprenoids and sterols [ 24 ] .

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