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It should be stressed that the true success rate of Ahab will be much higher since the number of genes for which blastoderm expression is demonstrated is (< 100) or 1/3 of the total.

More strikingly, the 10 modules for which experimental results in [ 6 ] suggest functionality based on blastoderm expression of a neighboring gene fall below 500 in our ranking with exception of giant and one of the hairy derived modules for nub, Table 4.

We collected from the experimental literature modules that drive blastoderm specific expression of a reporter gene in response to several of the factors in our list.

Cleavage in this species is meroblastic, furrows divide the blastoderm similar to the teleosts.

Unlike the teleostean pattern, however, the cleavage furrows continue past the blastoderm margin as grooves in the yolk cell surface.

The second furrow proceeds like the first, dividing the blastoderm deeply and extending past its margin outward across the gray yolk cell.

The first cleavage groove extends to the egg's equator by now, while the second meets the blastoderm margin.

Dissection shows that the deep blastoderm cells are still connected to the yolk cell, and appear to bud from it.

3D) - The surface of the blastoderm has acquired a lumpy appearance, which indicates the steady decrease in blastomere size.

Superficial blastomeres are tiny and the blastoderm surface consists of a thin enveloping layer, similar to that in teleosts.

In many specimens, the blastoderm forms a peaked mound at the animal pole.

The blastoderm has an irregular rim and a flat bottom where it joins the yolk cell.

3F) - The blastoderm begins epiboly by 36 hours at 18°, but has not reached the egg's equator.

Some specimens show the first indication of dorsal/ventral asymmetry, as a result of a lag in epiboly of the dorsal blastoderm margin.

This produces a slight bulge in the blastoderm margin at that location, as though epiboly were being retarded by its attachment to the yolk cell.

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