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English words and Examples of Usage
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Sentences for "carcinogenicity "
Potential applications beyond diagnosis and prognosis are diverse, and include treatment response stratification of patients in clinical trials, assessment of relevance to human safety of drug-associated tumors in animal carcinogenicity studies, and the development of more pertinent animal xenograft models of cancer therapy.
As an additional validation, each model was tested with a large group of structurally diverse molecules, which were taken from the FDA rodent carcinogenicity database [ 35 ] .
Possible side effects of the drug candidates were assessed by testing each candidate and its predicted metabolites against carcinogenicity and mutagenicity databases [ 35 ] , [ 36 ] .
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