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Sentences for "celiac "
txt Background Celiac disease (CD) is a common, familial, autoimmune gastrointestinal disease.
Methods Ascertainment of families with CD Families with at least two cases of CD or dermatitis herpetiformis were ascertained through local gastroenterologists, gluten intolerance support groups, and advertising at local and national celiac disease support meetings.
We were interested in identifying non-HLA loci for celiac disease.
This is similar to the experience in most other reported studies of celiac disease.
txt Most patients with celiac disease can eliminate their symptoms-at a price: life-long adherence to a gluten-free diet.
Then some recent studies suggested that oats did not cause the intestinal inflammation characteristic of the disease, and thus oats are now often included in the celiac disease diet.
In individuals with celiac disease, the immune system mounts an abnormal response to gluten, which is characterized by gluten-reactive intestinal T cells and by inflammation and compromised function of the small intestine.
Ludvig Sollid and colleagues applied the current understanding of celiac disease and a range of molecular pathology tools to studying the response to oats of nine patients with celiac disease.
Three of the four patients who had reported problems after eating oats showed intestinal inflammation typical of celiac disease, and Sollid and colleagues studied intestinal T cells from these three patients.
Taken together, the findings show that intolerance to oats exists at least in some patients with celiac disease, and that those patients have the same molecular reaction to oats that other patients have to wheat, barley, or rye.
Oats are not safe for all patients with celiac disease, but future studies are needed to determine the frequency of oats intolerance.
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