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Sentences for "chemotactic "
IL-8 is a potent chemotactic factor for granulocytes and T lymphocytes, and is found in HIV-infected individuals.
txt Background Model of an oscillating biochemical network In [ 8 ] , Laub and Loomis propose a model of the molecular network underlying adenosine 3',5'-cyclic monophosphate (cAMP) oscillations observed in fields of chemotactic Dictyostelium discoideum cells.
Besides platelets stimulated by various agonists such as thrombin with collagen or the complement complex C5b-9 [ 7 11 ] , a release of PS-containing membrane MP was demonstrated in other cell types such as endotoxin-stimulated monocytes [ 12 ] , polymorphonuclear leucocytes stimulated with the chemotactic peptide FMLP [ 13 ] or apoptotic T-lymphocytes [ 14 ] .
The first evidence that chemokines are associated with wound healing in vivo was reported in 1990 using the chemokine cCAF (chicken Chemotactic and Angiogenic Factor, the product of the 9E3 gene), a CXC chemokine that is now known to be the ortologue for human IL-8 [ 9 ] .
Another chemokine that has been associated with Coll I production is monocyte chemotactic protein 1 (MCP-1).
List of abbreviations used cCAF chicken Chemotactic and Angiogenic Factor CEFs chicken embryo fibroblasts Coll collagen ECM extracellular matrix FN fibronectin IL-8 interleukin-8 MCP-1 monocyte chemotactic protein-1 MGSA melanoma growth stimulatory activity MMP matrix metalloprotease PA plasminogen activator TGFß1 transforming growth factor ß1 TIMP tissue inhibitor of metalloprotease TN tenascin
The 3xAla myosin cells also display severe defects in chemotactic cell migration, demonstrating the importance of proper myosin II assembly dynamics in this process [ 12 ] .
They are likely to function as sensors of diffusible gaseous ligands that activate at least three distinct, downstream signaling pathways: namely phosphotransfer through the two-component systems, methyl ester-dependent chemotactic response and cyclic nucleotide signaling through the diguanylate cyclases/phosphodiesterases.
carinii has been shown to be a chemotactic factor for macrophages and monocytes in vitro [ 5].
Neither chemotactic processes, nor directed growth appear to be at play.
As an additional example RP S19, which is also down-regulated by NGF, has been implicated in erythropoiesis and has also been described as a monocyte chemotactic factor [ 46 ] .
The chemotactic cytokines, or chemokines, compose a large superfamily of small structurally related polypeptides that play important roles in host defense by recruiting specific subsets of leukocytes to sites of inflammation and injury [ 6 ] .
IGF-I produces a chemotactic response in human melanoma cells and antisense to the IGF-IR mRNA prevents metastasis in the murine carcinoma cell H-59.
The consequence of CD26 loss is unclear, CD26 modulates the action of many molecules including the chemotactic activity of some chemokine important for T-cell migration to skin [ 17 18 ] .
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