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Example Sentences for "chemotherapeutic "


It has been suggested that a dysregulation of MAP kinases is responsible for the growth factor deprivation [ 15 ] or chemotherapeutic agent [ 16 ] induced PCD.

Similarly, in studying the effect of an intense chemotherapeutic regimen for cancer on survival, the type of antibiotic should not change of over time, as new and more effective antibiotics could lower treatment-related mortality irrespective of the efficacy of the anticancer regimen.

[ 28 ] Timed sequential therapy has been employed in relapsed and de novo acute leukemia and achieves complete remission rates comparable to those achieved with other salvage chemotherapeutic regimens.

We report the results of a clinical trial assessing the potential benefit of adding G-CSF to a proven timed sequential chemotherapeutic regimen.

[ 27 ] Our results are comparable to those achieved with other salvage chemotherapeutic regimens that employ high-dose cytarabine.

IGF-IR-/- cells can proliferate in monolayers in the presence of serum but undergo apoptosis when put in suspension and are more sensitive to chemotherapeutic reagents.

In recent years it has become evident that nonsteroidal anti-inflammatory drugs (NSAIDs) represent a potential class of cancer chemotherapeutic agents.

They also raise into question the efficacy of aspirin as a chemotherapeutic for colon cancer, and perhaps more specifically, familial adenomatous polyposis.

Conclusions Despite abundant evidence from epidemiological, clinical and animal studies regarding the potential utility of aspirin as a chemotherapeutic agent for colorectal cancer, the current study found no change in tumour burden in the extensively used Min /+ murine model of colon cancer.

txt Background Although a number of recently introduced chemotherapeutic agents have demonstrated significant anti-tumor activity in advanced colorectal cancer, [ 1 2 3 4 5 6 7 8 9 ] standard therapy for patients with metastatic disease remains 5-fluorouracil (5-FU) - based chemotherapy.

The determination of the number of patients required in a preliminary and a follow-up trial of a new chemotherapeutic agent.

Moreover, if some chemotherapeutic agents are not only directly cytotoxic to cancer cells, but also reduce tumor production of growth factors, such as IGF2 and TGFß, adjuvant chemotherapy would be more useful in treating tumors with a mutated M6P/IGF2R , as observed in this study.

Currently there are no effective chemotherapeutic agents against cryptosporidiosis [ 5 ] .

a population attributable fraction of 85%, is noteworthy, especially since there are no effective chemotherapeutic agents against cryptosporidiosis [ 5 ] .

As a result, its cancer chemotherapeutic activities are under evaluation in Phase I human clinical trials [ 38 39 ] .

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