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Sentences for "chloroquine "
LysoTracker Red DND-99 is a chloroquine analogue that had been reported to selectively accumulate in acidic lysosomes [ 9 ] .
[ 26 ] Other quinoline derivatives (chiefly chloroquine and quinine) are the commonest co-medications mentioned in the case reports.
Munera et al described a woman with hypothyroidism, well stabilised on thyroxine sodium 125 µg daily, who took prophylactic chloroquine and proguanil daily for 2 months for a vacation in Africa.
Re-challenge with chloroquine and proguanil a year later again resulted in raised levels of TSH, a lowered concentration of free triiodothyronine (T 3 ), and normal free thyroxine (T 4 ) concentration.
[ 51 ] They also suggested that chloroquine might act centrally on the hypothalamus, through disruption of the feedback system by which thyrotropin releasing hormone stimulates the pituitary to release and later synthesise TSH.
[ 52 ] A third mechanism by which chloroquine and chemically related drugs such as mefloquine might interfere with thyroid function is through structural homology to T 3 , resulting in thyroid hormone antagonism.
The use of marijuana and other psychoactive agents by chloroquine users has been associated with acute psychotic reactions, and it has been suggested that mefloquine users who take recreational drugs may likewise be predisposed to neuropsychiatric problems.
In August 1998 the Government of Kenya changed its first-line anti-malarial treatment from chloroquine to sulfadoxine-pyrimethamine (SP) [ 10 ] .
A gazette notice in October 1999 permitted SP to be sold over the counter and required that chloroquine be sold only by prescription.
However, because of lack of enforcement, the 28 unapproved SP drugs still remained in the market, as well as chloroquine and amodiaquine.
List of abbreviations used AMREF African Medical Research and Education Foundation AQ amodiaquine ANOVA analysis of variance CQ chloroquine DHMT District Health Management Team QAP Quality Assurance Project SP sulfadoxine-pyrimethamine USAID United States Agency for International Development WHO World Health Organization Authors' contributions PT conceived the study, performed most of the data analysis, and drafted the results and discussion sections of the manuscript.
He was also receiving chloroquine for malaria.
Proquanil with chloroquine have been advised as the best prophylactic regimen for tourists travelling to the southeast Anatolia region of Turkey between March and November [ 9].
Here, without an industrial partner, Krogstad and colleagues are using in-house chemistry and computational assistance to modify chloroquine analogs in an effort to overcome the problem of chloroquine resistance in malaria treatment.
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