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Sentences for "chondroitin "
, the presence of heparin, HS, and chondroitin sulfates with heparinase, heparitinase, and chondroitin ABC respectively.
For the chondroitinase ABC reactions, each chondroitin sulfates A, B and C substrate (1 mg each) and concentrated CM, were incubated with 0.
For example, heparin, heparan sulfate, and dermatan sulfate all contain iduronic acid residues whereas chondroitin sulfate and hyaluronic acid do not.
This result is consistent with the idea that HSPGs but not chondroitin sulfate proteoglycans serve as signaling receptors for III1-C.
In addition, inhibition by heparin, heparan-sulfate, and heparitinase, but not by chondroitin sulfates or chondroitinase ABC all point to the importance of HSPGs as receptors.
In contrast, when tissue disruption was significant and accompanied by glial scarring, including astrogliosis and the upregulation of chondroitin sulfate proteoglycans (CSPGs), axonal growth stopped in areas of CSPG expression.
CSPG immunohistochemistry Chondroitin sulfate proteoglycan (CSPG) staining was carried out in adjacent spinal cord sections using the monoclonal antibody CS-56 raised against chicken chondroitin sulfate.
Additional investigations identified myelin-associated molecules, including Nogo (formerly NI-35/250), myelin-associated glycoprotein (MAG), and chondroitin sulfate proteoglycans, that inhibit neurite growth [ 10, 11, 12, 13, 14, 15, 16, 17, 18, 19].
Media was was collected daily and analyzed for GAG release by the dimethylmethylene blue (DMMB) assay using purified shark chondroitin sulfate (Sigma Chemical) as the reference standard.
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