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Sentences for "cirrhosis "
Too much alcohol may cause cirrhosis of the liver, inflammation of the pancreas, and damage to the brain and heart.
Five hepatitis C health states (HS) were described ranging from HS1-No Symptoms, No Cirrhosis to HS5-Severe Symptoms, Cirrhosis (Table 1).
We designated life without hepatitis C as the highest preference value and assessed preferences for the health state hepatitis C with No Symptoms, No cirrhosis because the psychological impact of having a disease can effect health status in the absence of physical symptoms.
The median preference value for HS1-No Symptoms, No Cirrhosis was 88% (interquartile range 75%-95%) corresponding to a 12% reduction from life without hepatitis C.
The long-term sequelae of chronic HCV infections include increased risks of liver cirrhosis and hepatocellular carcinoma [ 4 5 ] .
Twenty-six probands (20 men, 6 women) had hepatic cirrhosis demonstrated by hepatic biopsy.
txt Background Cirrhosis is a pathologic condition characterized by fibrosis of the liver parenchyma and evidence of regenerative activity [ 1 ] .
The epidemiology of cirrhosis is linked to both alcohol consumption [ 2 3 4 5 ] and the prevalence of hepatitis B and hepatitis C virus infections [ 5 ] .
The diagnosis of cirrhosis has both prognostic and therapeutic implications [ 7 ] .
The life expectancies for persons diagnosed with cirrhosis are significantly reduced [ 8 9 10 11 ] compared with age and sex-matched controls, with the exception of certain pathological subtypes [ 12 ] .
The patchy or regional nature of hepatic changes means that percutaneous liver biopsies may miss the diagnosis of cirrhosis in 24 percent of patients with the condition [ 23 ] .
Given the invasive nature of the diagnostic standard, there has been interest in whether non-invasive diagnosis of cirrhosis might be possible [ 13 24 ] .
This study was conducted to review the published literature on clinical examination of patients with known or suspected liver disease and identify the validity and generalizability of primary studies that distinguished those with cirrhosis from those without.
Additional articles were sought by scanning bibliographies in standard reference textbooks, proceedings of meetings or conferences on cirrhosis or liver disease, the reference sections of selected articles or review articles on liver disease, cirrhosis, or physical examination, or other potentially relevant chapters in books.
The reference standard for diagnosis of cirrhosis was histological evidence of irreversible chronic injury to liver parenchyma with extensive fibrosis and formation of regenerative nodules.
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