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Sentences for "citrulline "
It was hypothesized that the NARP mutation would cause complex V deficiency in the small intestine as well, thus reducing the availability of mitochondrial ATP required for citrulline synthesis.
A potential explanation for this may relate to the demonstration that citrulline appears to be an essential constituent of the antigenic determinants recognized by AKA, APF, and AFA.
The citrulline rich (pro)filaggrin molecule makes an ideal substrate for detecting this reactivity.
These proteins follow a common post-translational pathway, which involves a peptidyl-arginine to citrulline deimination.
Antibodies to CCP were evaluated after generating a cyclic peptide from linear citrulline containing peptides, by substituting serine residues by cysteine.
A potential explanation for this may relate to the demonstration that citrulline appears to be an essential constituent of the antigenic determinants recognized by AKA, APF, and AFA [ 16, 17].
The citrulline rich (pro)filaggrin molecule makes an ideal substrate for detecting this reactivity.
Moreover, there was a spectrum of reactivity patterns seen when RA sera were tested against various citrulline containing peptides [ 17].
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