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Example Sentences for "cog "


She was a pork-barreler and a more-or-less willing cog in the Queens Democratic machine.

John Huang was merely a cog in this machine.

" Contrary to the Gatorade ad, the magazine reports with admiration that Hamm "sees herself as a solid cog in a remarkably powerful machine" and "refuses to acknowledge that she's a player with unique gifts.

A survey of the COG data set identified 132 COGs, each of which included a large number of bacterial and archaeal species, but no or few paralogs and thus appeared to be amenable to a large-scale phylogenetic analysis (Table 11).

The COG construction procedure does not rely on any preconceived phylogenetic tree of the included species except that certain obviously related genomes (for example, two species of mycoplasmas or pyrococci) were grouped prior to the analysis, to eliminate strong dependence between BeTs.

This method for identification of probable orthologs is, in principle, similar to the method employed in COG construction, but differs in that there is no requirement for the formation of triangles of consistent BeTs.

However, the limitation of the COG system, namely the requirement that each orthologous group is represented in at least three genomes, is avoided.

Maximum Likelihood trees based on concatenated alignments of ribosomal proteins Sets of orthologous ribosomal proteins were extracted from the COG database, and their amino acid sequences were aligned using the T-Coffee program [ 45 ] , with subsequent manual validation and removal of poorly aligned regions.

Comparative analysis of Maximum Likelihood trees for individual protein families The representative families were selected from the COG database according to the following criteria: i) at least 30 species are represented, ii) no more than two paralogs in any of the species, iii) no more than 1.

Functional assignments using the COG database Datasets for QuartOPs with strong preference for a particular tree topology (i.

For each of those QuartOPs the COG functional category [ 27 ] was identified.

In order to detect the functional categories, the COG database was downloaded from NCBI's FTP site (initially the year 2000 release and later the year 2001 release).

The COG database was formatted using the formatdb program of BLAST package.

Every QuartOP was compared to the COG database using the blastp program.

Distribution of ORFs among COG categories for complete genomes of Halobacterium sp.

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