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Example Sentences for "collagen "


So it was comforting this week to be told by the Star that Melanie Griffith's bee-stung lips "appear to be the result of collagen overload," and by the Globe that Shaquille O'Neal supposedly just had breast-reduction surgery.

) How does Harris know whether his models have had collagen injections and nose jobs?

Although neither sample adhered to collagen to the same extent as to fibronectin, vector only controls adhered more strongly than IDO-expressing clone 11 (Fig 3B).

IDO axpression alters metalloproteinase expression The altered adhesion of IDO-expressing RAW cells to collagen suggested that IDO might induce alterations in enzymes involved in modifying the extracellular matrix.

Collagen is one of the principal components of the extracellular matrix and RAW cells bind poorly to fibrillar type I collagen unless it is denatured or activated by collagenase [ 38].

However, it should be emphasized that these experiments involved growing EC on plastic, not on layers of subendothelial matrix components such as collagen or fibrinogen.

In the absence of SPARC, expression of transforming growth factor-ß1 and type I collagen is down-regulated in kidney mesangial cells [ 15 ] .

It has been reported [ 28 ] that fibroblasts incorporated in a collagen gel induce progressive contraction of the gel, resulting in the formation of a dense collagen disc of greatly reduced diameter.

Gel diameter was measured at various time points following incorporation of fibroblasts in the collagen gel, and the area calculated and expressed as a percentage of the initial area.

Primary dermal fibroblasts from SPARC-null mice contracted type I collagen gels as efficiently as primary dermal fibroblasts from wild-type mice, contracting to 30% of the initial area at 20 hours and to 15% by 40 hours after incubation of the fibroblasts in collagen gels (Fig.

We showed in the present study that there are no overt differences in cell proliferation and type I collagen gel contraction between control and SPARC-null dermal fibroblasts.

Northern analysis of wound biopsies showed that production of type I collagen and fibronectin by the null mice, at the beginning of wound healing, was lower than that by the wild-type mice.

Subsequently, the wound in the null mice was fully invaded by fibroblasts and expression of type I collagen and fibronectin by the SPARC-null mice was as abundant as that by the wild-type mice.

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