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Performing the GO analysis one gene at a time would have taken more than two solid hours at the computer for the 181 genes before getting to the much harder parts of the task: doing the same for the entire array (nominally > 15 hours), then collating and organizing the information for each GO category.
William Bateson, late Professor of Biology in the University of Cambridge, as early as 1894 laid great stress on the importance of discontinuous variations, collecting and collating the known facts in his “Materials for the Study of Variations”, but this important work, now become rare and valuable, at the time excited so little interest as to be ‘remaindered’ within a very few years after publication.
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