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Sentences for "colonic "
Some laugh at colonic humor, some don't.
-- Charles Waugh Ex-Cons Find A Drag Racer Touching and Fondling NRA's Favorite Hobbyhorse Wall Street Journal , May 25, 1999 -- Tim Carvell Common Denominator Colonic discomfort.
MAdCAM-1 has also been detected at high levels on colonic lamina propria venules from mice with hapten induced colitis [ 14], mice injected with TNF-?
[ 15], or colitic IL-2 knockout mice [ 16].
, [ 26] found that iNOS expression was significantly increased in colonic epithelia from individuals with IBD.
Because of this prime role of TNF-?
in IBD, anti-TNF-?
antibody therapy has been very successfully used in IBD to reduce both colonic injury and expression of ECAMs in IBD [ 51 ] .
Due to this, interpretation of colonic biopsies for intestinal A-GVHD may be a major diagnostic challenge especially for those not conversant with these findings [ 10 ] .
However, the distribution pattern of apoptosis in colonic mucosa in A-GVHD has not been methodically evaluated.
The histopathology was negative for any diagnostic pathology with nonspecific changes or normal colonic mucosa.
Other negative control group desired would be colonic biopsies from the cases undergoing all the therapy components of BMT including cytoreductive therapy but without BMT.
Discussion Some of the histological features of A-GVHD in colonic biopsies have been studied and reported previously [ 6 11 14 23 ] .
Whether or not this phenomenon may be reproduced with other IFNg-resistant colon carcinoma cell lines is of particular interest, since colonic epithelium is physiologically exposed to PKC activators that enhance cytokine signalling in enterocytes during inflammatory responses within the intestinal mucosa [ 42 ] .
Over-expression of PDGFR has been reported in a variety of human tumors including glioma and glioblastoma, pancreatic and colonic cancers, breast, bone and ovarian tumors [ 11 ] .
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