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Sentences for "compaction "
Although all domains in midasin have yielded something to the pressure for gene compaction during evolution of Encephalitozoon, it is the N-terminal, linker and D/E-rich domains, in which the sequence is relatively less conserved among organisms, that have yielded the most.
In concordance with previous investigations [ 10 ] , it was found that the rate of lens compaction was not constant over time, and that the majority of compaction was observed before middle age.
In this study, SEM was used to search for evidence of osmotic swelling and/or fiber cell compaction in the nucleus of non-cataractous and clinically diagnosed nuclear cataractous human lenses from persons with diabetes.
For further comparisons, previously documented non-diabetic compaction data was utilized [ 4 ] .
Morphometry To detect differences in the extent of compaction between transparent and cataractous diabetic lenses, some of the same analysis procedures outlined in our previous SEM compaction study were used [ 4 ] .
average number of embryonic nuclear fiber compaction folds over a 20 µm distance (2000 X).
To determine the mean number of membrane compaction folds on the surface of EN fiber cells over a 20 µm distance, five to ten measurements per sample were compiled and averaged.
Comparisons between diabetic and non-diabetic lenses To detect any changes in compaction due to diabetes itself, morphometric data from non-diabetic aged transparent human lenses (ages 59-81) and non-diabetic age-related nuclear cataracts (ages 55-81) were utilized for additional statistical comparisons [ 4 ] .
As observed in non-diabetic aged transparent and age-related human cataractous lenses, it appears that nuclear fiber cell compaction is responsible for these differences.
To relate these variations in compaction to diabetes and/or cataractogenesis, statistical testing was performed using previously collected non-diabetic data.
Parameter comparisons of transparent aged human lenses to those of diabetics did not yield statistically significant results, indicating little difference in average nuclear compaction between the tissues.
This suggests that the compaction changes observed in this study are not necessarily a direct effect of diabetes itself, but are perhaps due to morphological changes in the nuclei undergoing cataractogenesis.
Although the exact details concerning the cause of compaction remain unknown, some features of the multifactorial process are understood.
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