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Sentences for "compartmentalization "
Subcellular compartmentalization of SCF Popas a potential mechanism for substrate selection Another surprising observation of this study was that Pop1p is primarily localized to the nucleus, whereas Pop2p is present in both the cytoplasm and the nucleus (Fig.
The idea developed above that F-box protein compartmentalization contributes to substrate selection was recently confirmed directly for Cdc4p-mediated degradation of Far1p in budding yeast [ 35 ] .
Previous findings indicate a complex, cell-type dependent regulation of compartmentalization and intracellular pools of thiamine and its phosphorylated derivatives in response to fluctuating extracellular thiamine levels [ 4 5 6 ] .
Previous studies indicate the existence of a complex, cell-type dependent regulation of compartmentalization and intracellular pools of thiamine and/or its phosphorylated derivatives in response to fluctuating extracellular thiamine levels [ 4 6 17 ] .
The method described is envisioned to broaden biological applications of ultrastructural immunogold labeling techniques especially in investigations dealing with compartmentalization of functional elements.
No difference in compartmentalization or staining intensity in cells was observed as a function of cell or bud size.
It has been known for the past decade that compartmentalization of PKA can occur through association with A-kinase anchoring proteins (AKAPs).
The work reported here was undertaken to further understand the compartmentalization of PKA and PKC through association with AKAPs.
Our interest in PKA and PKC activity in the NMJ derives from: (1) a report that RI?
not only is enriched there, but also appears to be tethered to the postsynaptic membrane [ 19 ] , (2) the rich literature describing selective PKC isoform activity and functional compartmentalization in the NMJ and skeletal muscle, (3) our discoveries that D-AKAP1 and D-AKAP2 bind to and appear to colocalize with RI?
, and often mitochondria [ 15 16 28 ] , and (4) our finding that gravin binds to both PKA and PKC [ 13 ] .
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