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Sentences for "constitutive "
The constitutive membrane of the adult oogonia is reabsorbed in a great many points, and is there pierced with rounded holes.
If experimental inquiry leads to affirmative answers to the questions, we shall have to think of atoms as structures of particles much lighter than themselves; we shall have to think of the atoms of all kinds of substances, however much the substances differ chemically and physically, as collocations of identical particles; we shall have to think of the properties of atoms as conditioned, in our final analysis, by the number and the arrangement of their constitutive electrons.
But I know no justification for this transference of the conceptions of chemistry to psychology;[32] I know no reason for considering psychical antecedents as really constitutive of their psychical consequents, in spite of the apparent dissimilarity between the two.
And, generally, when a constitutional rule has to be elicited from a comparison of precedents, it is open to dispute whether a particular act of either party should be regarded as a constitutive precedent or as an illegitimate encroachment.
Thus, specificity for constitutive association with CD98 may reside in integrin ?
chain extracellular or transmembrane domains.
Notably, 2 mM EDTA had no inhibitory effect on constitutive integrin-CD98 associations (not shown).
Results Constitutive overexpression of IDO alters cell adhesion To determine whether IDO plays a role in regulating cell adhesion, we expressed a full-length IDO cDNA in cell lines in vitro .
Therefore, we investigated whether inhibition of IDO expression in the P19 in vitro aggregation system and the constitutive overexpression of IDO in RAW cells had any effect on MMP expression.
Paul Insel, UCSD) demonstrated constitutive activation of ERKs when both are grown at low density (not shown).
Furthermore, experimentally it was shown that constitutive expression of the glyoxylate bypass suppressed the PEP deficient phenotype [ 30, 31].
Stable cell lines containing the mutant proteins are inducible with Tet and show altered localization The cell lines chosen for study contain some constitutive expression of the BLM alleles but show good reproducible induction (Table I).
The N-terminal deletion alleles have higher levels of constitutive expression relative to the C-terminal mutations and have overall higher levels of protein expression, one explanation is that the C-terminal mutations are deleterious.
The BS cell line used here lacks BLM [ 10] and all cell lines obtained from transfection of the normal GFP-BLM gene had a background level of constitutive expression leading to a partially corrected SCE frequency relative to the parental line (40 vs.
Despite the time and effort required to screen multiple clones, some with constitutive levels of expression, experimentally useful cell lines were obtained that allowed investigation of the function of the N-terminus and C-terminus of BLM.
The Tet-inducible system shows better SCE correction than constitutive expression Our previous study used stable transfected cell lines derived from the same SV40-transformed BS cell line used here, except that the normal and missense alleles of BLM were expressed from a constitutive promoter [ 10].
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