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gov/Microb_blast/yielded additional sequences in the genomes of Corynebacterium diphtheriae , Mycobacterium avium , M.

PCC 7120, Ap: Aeropyrum pernix , At: Arabidopsis thaliana , Atu: Agrobacterium tumefaciens , Ban: Bacillus anthracis , Bb: Borrelia burgdorferi , Bha: Bacillus halodurans , BPRB49: Bacteriophage RB49, Bs: Bacillus subtilis , Cac: Clostridium acetobutylicum , Cau: Chloroflexus aurantiacus , Ccr: Caulobacter crescentus , Ce: Caenorhabditis elegans , Chte: Chlorobium tepidum , Cgl: Corynebacterium glutamicum , Cpe: Clostridium perfringens , Ddi: Dictyostelium discoideum , Dm: Drosophila melanogaster , Ec: Escherichia coli , Gme: Geobacter metallireducens , Hi: Haemophilus influenzae , Hs: Homo sapiens , Hsp: Halobacterium sp.

Database searches revealed that Rv0365c encodes an ~41-kDa protein which displays significant homology only to a truncated Corynebacterium glutamicum hypothetical protein of unknown function (42% identity in a 296 aa overlap) located upstream of a gene encoding a fructose-bisphosphate aldolase.

Rv0365c encodes a hypothetical protein of 376 amino acids which displays significant homology only to a Corynebacterium glutamicum hypothetical protein of unknown function (42% identity in a 296 aa overlap) [ 23 ] .

Blood isolates of coagulase-negative staphylococci, Corynebacterium species, Bacillus species, Propionibacterium species, Peptostreptococcus species, Clostridium species, and unidentified Gram-positive rods were considered contaminated if a single blood culture yielded the organism or the clinician did not initiate treatment, considering it not a true infection.

Additionally, a search of the NR database with a position-specific scoring matrix (PSSM) that included all unique RDRP and YRH sequences detected, with borderline E-values, a large protein from Corynebacterium glutamicum (Cgl1702), which also contained a DXDGD motif.

The Cgl1702 protein from Corynebacterium , which we identified as one of the most divergent members of the DDRP clade, showed similarity to the other DDRPs only in two regions, which corresponded to the DPBBs from the ß and the ß' subunit.

Ancient conserved domains and evolution of DNA-dependent RNA polymerases While all bacteria, archaea and eukaryotes encode orthologs of at least four distinct subunits of DDRP, the divergent RNA polymerases of baculoviruses and yeast killer plasmids and the Corynebacterium Cgl1702 protein only contain counterparts to the ß and ß' subunits.

barkeri, Rhodobacter capsulatus, Chlamydia psittaci, and Corynebacterium diphtheriae ) possess two copies of TrpEb_1.


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