Driving under the influence of alcohol is a major factor in many automobile accidents.
Alcohol was a major factor in a car accident which claimed three lives over the weekend.
Recent research suggests that environment is the major factor underlying the increase in cancers in our society.
Laughter helps us to connect with others and counteracts feelings of alienation, a major factor in depression and suicide.
Research by Leki and Carson has shown that second language learners see lack of vocabulary as the major factor affecting the quality of their writing.
Inconsistency and injuries on the offensive line were a major factor.
This may not seem like much but it could be a major factor in weight regain over time.
The striker, who bagged 13 goals last season, was a major factor in the team’s turnaround.
Oil’s bounce back could play a major factor in the markets success or suffering this summer.